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A method for the selection of bacterial strains overproducing exopolysaccharides

A method for the selection of bacterial strains overproducing exopolysaccharides (EPS), carbohydrate polymers that are secreted into the environment.

Méthode de sélection de souches bactériennes surproduisant des exopolysaccharides
Updated on 03/27/2018
Published on 02/27/2018

Using Lactobacillus rhamnosus, scientists in the the INRA-AgroParisTech Joint Research Unit for Food and Gut Microbiology for Human Health (UMR MICALIS)  have developed a method to isolate bacteria that overproduce EPS.

Lactobacillus rhamnosus is used for its organoleptic properties in the production of yoghurts and cheeses. And because of its health benefits, it is also used in dairy products for children and infants. Its resistance to a low pH and its adhesion to the gastrointestinal tract are additional properties of considerable interest.

The innovation of the method proposed is that it is possible to isolate spontaneous non-GM and non-pathogenic mutants while preserving the acknowledged safety of the strain (QPS/GRAS).

The method could be applied to other bacteria, thus opening the way to wide-ranging applications in foods, cosmetics and health.

Advantages

  • Non-GM strain
  • Bacteria already used as a lactic ferment
  • The method can be adapted to other bacteria

Applications

  • Foods: a new ferment to give texture to foods (emulsifier, thickening agent)
  • Health: immune-stimulating, anti-tumour, prebiotic properties
  • Cosmetics: moisturising and anti-allergic properties

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Contact(s)
Inra transfert Valorisation Manager:
Héloïse Simonson (+33 (0)6 47 05 15 98)

Type of transfer

License on know-how or licensing option with R&D programme (TRL 2)