In the framework of the European Conference on Computational Biology
(ECCB), we organize a satellite
meeting on the modeling and simulation of biological regulatory
processes. Although the focus will be on the
mathematical and computational analysis of genetic regulatory networks,
we also wish to establish links with related work on metabolic and
signal transduction networks. The aim of the satellite meeting is, on
the one hand, to provide a forum for computational biologists to
discuss methods and computer tools available for the dynamical analysis
of biological regulatory processes. On the other hand, we would like to
bring together computational and experimental biologists in order to
foster collaborations leading to useful applications of the methods and
tools.
The satellite meeting has a duration of one day, immediately after the
ECCB conference (October 1, 2003). It will take place at the Ecole Normale Supérieure of Paris, in the Dussane lecture room (see
below for access). From the submissions received, seven abstracts have
been selected for a presentation of 20 minutes. Four invited
presentations of 40 minutes and two plenary discussions of 30 minutes
complete the program. The abstracts of the presentations will appear in
the proceedings of the satellite meeting distributed to the registered
participants.
If you wish to attend the satellite meeting,
please send an e-mail to Hidde.de-Jong@inrialpes.fr. No registration fees are required. Because
the number of participants is limited due to space restrictions, we
recommend you to register as soon as possible.
A preliminary version of
the program is shown below.
|
9:00-9:30 |
Registration |
|
9:30-9:40 |
Welcoming speech |
|
9:40-10:20 |
Modeling of cell cycle
control in budding yeast - L. Calzone (Virginia Polytechnic
Institute and State University) |
|
10:20-10:40 |
Effects of stochasticity in
models of the cell cycle: From quantized cycle times to
noise-induced oscillations - R. Steuer (Potsdam University) |
|
10:40-11:00 |
Coffee break |
|
11:00-11:40 |
Deterministic versus
stochastic models for circadian rhythms - D. Gonze, J. Halloy, A.
Goldbeter (Université Libre de Bruxelles) |
|
11:40-12:00 |
Formal validation of models
of genetic regulatory networks - G. Batt, H. de Jong
(INRIA Rhône-Alpes), J. Geiselmann (Université Joseph Fourier), M.
Page (INRIA Rhône-Alpes and Université Pierre Mendès France) |
|
12:00-12:20 |
Temporal logics and biological
regulatory networks - G. Bernot (Université d'Evry), O. Roux (Ecole Centrale
Nantes), C.
Auberger, V. Bassano (Université d'Evry), F. Cassez (Ecole
Centrale Nantes),
J.-P. Comet, F. Delaplace, A. Richard (Université d'Evry), O. Roux (Ecole Centrale
Nantes), F. Tahi
(Université d'Evry) |
|
12:20-12:40 |
Plenary discussion |
|
12:40-14:00 |
Lunch break |
|
14:00-14:40 |
Improving inference of genetic
regulatory networks from time-course microarray data - E. van
Someren (Delft University of Technology) |
|
14:40-15:00 |
Bottom up or top down?
Computational methods for determining complex biochemical reaction
networks - E. Crampin (University of Oxford and University of
Auckland), S. Schnell, P. McSharry (University of Oxford) |
|
15:00-15:20 |
Hybrid concurrent constraint
programming: A well-suited formalism for modelling alternative splicing
regulation - D. Eveillard, A. Courtois, A. Bockmayr (LORIA and
Université Henri Poincaré) |
|
15:20-15:40 |
Coffee break |
|
15:40-16:20 |
Control of proteolysis of RpoS,
the master regulator of the general stress response in E.coli, by a dynamic switch mechanism
based on multiple feedback - R. Hengge (Freie Universität Berlin) |
|
16:20-16:40 |
Modelling and simulating the
regulatory network specifying the Notch boundary between the dorsal and
the ventral compartments of the wing imaginal disc- A.
González, C. Chaouiya, D. Thieffry (Université de la Méditerranée),
L. Sánchez (Centro de Investigaciones Biológicas, Madrid) |
|
16:40-17:00 |
A network model for the
mechanism controlling Th cell differentiation - L. Mendoza, M.
de Francesco (Serono Pharmaceutical Research Institute) |
|
17:00-17:30 |
Plenary discussion and
closing remarks |
The
French IMPG thematic group devoted to gene networks modelling will meet
on October 2, still at the ENS but in the room Favard (46 rue d'Ulm),
from 9h30 to 12h30. The meeting will be followed by a lunch at a nearby
"brasserie".
Practical
information about access to ENS and a map can be found at the URLs:
http://www.ens.fr/ecole/acces.html
http://www.ens.fr/ecole/plan.html
The Dussane room is in
the green building 6 on the map.
This workshop is part of the
activities of the IMPG working
group on Functional Bioinformatics of Genetic Regulatory Systems, coordinated by Bernard Jacq,
Claude Jacq, and Denis Thieffry. Funded by the French Ministry of
Research, the programme IMPG (for Informatique, Mathématique et
Physique pour la Génomique) aims at promoting and developing
interdisciplinary research at the interface of computer science,
mathematics, physics, and biology. It is currently composed of a dozen
working groups covering a variety of topics in bioinformatics.
Claude Jacq offers us hospitality at the Ecole Normale Supérieure of Paris.
This document was translated
from LATEX by HEVEA.