Welcome to ESSA Home Page !
ESSA is an integrated and interactive computer tool for analysing RNA secondary
structure.
SUMMARY
With ESSA, we propose an approach of RNA secondary structure analysis based
on extensive viewing within a friendly graphical interface. This computer
program is organized around the display of folding models produced by two
complementary methods suitable to draw long RNA molecules. Any feature
of interest can be managed directly on the display and highlighted by a
rich combination of colors and symbols with emphasis given to structural
probe accessibilities. ESSA includes also a word searching procedure allowing
an easy visual identification of structural features even complex and degenerated.
Analysis functions make it possible to calculate the thermodynamic stability
of any part of a folding using several models and compare homologous aligned
RNA both in primary and secondary structure. The predictive capacities
of ESSA which brings together the experimental, thermodynamic and comparative
methods, are increased by coupling it with a program dedicated to RNA folding
prediction based on constraints management and propagation.
AVAILABILITY
ESSA software is available for current UNIX workstations in laboratory
:
Hewlett-Packard (HP-UX 9.0 or later), Intel Linux (Kernel 2.2.5-15 or later), Silicon
Graphics (IRIX 5.3 or later), Sun (Solaris 2.4 or later).
LINK
ESSA Article in Nucleic Acids Research Journal
How to get ESSA ?
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Farid Chetouani Last Modification 22/08/2000