06 Jan 2017
The first ever cloned calves, in INRA’s Developmental Biology and Reproduction research unit in Jouy en Josas. © INRA, PAILLARD Gérard

Low birth rate after cloning: the consequences of highly disruptive interactions between uterus and embryo

When comparing cloned animal embryos and embryos that come about as a result of artificial insemination, there is a difference in gene expression at the moment implantation occurs in the uterus for more than 5 000 genes. Researchers at INRA and the University of California are shining the spotlight on this critical step for the survival of cloned embryos in cattle. Published in the 8 December 2016 issue of the journal Proceedings of the National Academy of Sciences, these findings are furthering knowledge of hitherto poorly-understood mechanisms that govern interactions between cloned embryos and the uterus. They may hold the key to improving cloning in mammals.

15 Dec 2016
09 Dec 2016
Media library

Most recent media:

  • Biofilm mixte de Lactococcus lactis (coques jaunes) et de Listeria monocytogenes (bâtonnets roses), observé en microscopie électronique à balayage.. © inra, Thierry MEYLHEUC
  • Supermarché. © MAITRE Christophe
  • Ciel d'orage en Eure et Loir.. © INRA, WEBER Jean
  • Floating market.. © INRA, Chloé Le Bastard
  • Céréales et tournesols fleuris sur fond de ciel.. © INRA, BEGUEY Alain