An olfactory receptor to determine agents for the control of Spodoptera littoralis

Spodoptera littoralis is a polyphagous pest widely present in Africa and southern Europe. It causes extensive damage to cotton crops, but also attacks numerous other cultivated plants.

Spodoptera littoralis is a polyphagous pest widely present in Africa and southern Europe © INRA
Updated on 08/23/2017
Published on 05/29/2017

Spodoptera littoralis is a polyphagous pest widely present in Africa and southern Europe. It causes extensive damage to cotton crops, but also attacks numerous other cultivated plants.
A team from the Institute of Ecology and Environmental Sciences in Paris has identified an “olfactory receptor/ligand” pairing whose specificity has been demonstrated in vivo using genetically-modified insects in which the candidate ligands (out of 50 molecules, only one was recognised by the target receptor) and candidate receptors (out of 20 receptors, only one recognised the target ligand) were tested.
This ligand is the principal component in the pheromone of Spodoptera littoralis and is alone sufficient to attract males of the species.

Contact(s)
Inra Transfert, Transfer Agent:
Claire Nodet

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Applications

  • Screening of agonists/antagonists
  • Development of “super-attractive” molecules (sexual confusion),
  • Crop protection (sexual trapping of males),
  • Determination of neighbouring receptors or extension to other species of potential applications.

Intellectual property

  • Patent family filed by INRA/CNRS/Université Pierre et Marie Curie
  • Priority date: 23 March 2016.
  • European patent application (EP16305329.1) under the Patent Cooperation Treaty (PCT).

Partnerships/Licenses

  • INRA Transfert is looking for partners interested in evaluating the efficacy of the molecule and/or developing and commercialising a product under a licensing agreement or an option to license with an R&D programme.